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Written by: Rafael Guimarães & Kristen DiFilippo, PhD, RDN

Malnutrition is a global public health crisis affecting millions of people, impacting not only physical health but also mental well-being. According to the Food and Agriculture Organization (FAO), approximately 828 million people were undernourished in 2021, a number that has grown due to rising food and economic crises (FAO, 2022). In the United States, about 13.5% of the population faces food insecurity, including 7.2 million children who lack regular access to nutritious foods (USDA, 2024).

This situation is concerning, as studies show that malnutrition is closely linked to an increased risk of mental health issues. According to the World Health Organization (WHO), approximately 15% of the global population lives with some form of mental health condition, and individuals facing malnutrition or food insecurity have a significantly higher risk of developing conditions such as depression and anxiety (WHO, 2021) . Research by (Chrzastek, Guligowska, Sobczuk, & Kostka, 2023) found that people with essential nutrient deficiencies have a 30% higher risk of developing depression symptoms over their lifetime. These statistics underscore the importance of understanding how malnutrition can profoundly and enduringly impact mental health.

How Does Malnutrition Affect Mental Health?

The brain is one of the most metabolically active organs and requires a variety of nutrients to function properly. When the body does not receive the necessary nutrients—whether due to insufficient intake or poor absorption—the brain can be severely impacted. Deficiencies in vitamins, minerals, and other nutrients are associated with various mental health conditions, including symptoms of anxiety and depression (Benton, 2010). A lack of essential nutrients disrupts neurotransmitter production and can impair cognitive and emotional functions.

  • Vitamin B12 and Folate: Deficiencies in vitamin B12 and folate are linked to symptoms such as fatigue, brain fog, and depression. These nutrients are essential for producing neurotransmitters like serotonin, which regulate mood and emotional well-being (Stabler, 2013). Studies indicate that individuals with a B12 deficiency have a 50% higher risk of developing depressive symptoms (Laird et al., 2023).
  • Iron: Iron deficiency, one of the most common nutritional deficiencies, is associated with cognitive issues, including concentration and memory difficulties. In severe cases, iron deficiency can lead to anemia, which is linked to a higher risk of depression and anxiety (Lee, Chao, Huang, Chen, & Yang, 2020).
  • Omega-3 Fatty Acids: These essential fatty acids, primarily found in fish, are crucial for brain health. Studies show that omega-3 deficiency is associated with an increased risk of depressive and anxiety disorders, especially in young adults (Parker et al., 2006).
  • Impact of Malnutrition on Children and Adolescents: Children and adolescents are particularly vulnerable to the effects of malnutrition. During development, the brain requires nutrients to support synapse formation, neural plasticity, and overall growth. When these nutrients are lacking, cognitive and emotional development is directly compromised (Prado & Dewey, 2014).
  • Child Malnutrition and Cognitive Problems: Chronic malnutrition in children leads to attention problems, learning difficulties, and poor school performance. Studies indicate that malnourished children are three times more likely to develop symptoms of anxiety and depression in adolescence and adulthood (Grantham-McGregor et al., 2007).
  • Impact on Socialization and Behavior: Children with nutritional deficiencies also show difficulties with socialization and behavioral regulation. Malnutrition can affect emotional regulation, leading to increased aggressive behavior and hyperactivity symptoms (Lu, Perez, Leslein, & Hatsu, 2019).
  • Malnutrition and Mental Health in Adults and Older Adults: In adults and older adults, malnutrition also plays a significant role in mental health. Beyond depressive symptoms, nutrient deficiencies in older individuals are associated with faster cognitive decline and an increased risk of dementia (van Soest et al., 2024).

Strategies to Mitigate the Impact of Malnutrition on Mental Health

Given the relationship between malnutrition and mental health, strategies focused on improving nutrition can positively impact both physical and mental health.

  • Supplementation Programs: In communities with a high prevalence of micronutrient deficiencies, supplementation programs providing essential vitamins and minerals can help mitigate the negative impacts of malnutrition on mental health (Bailey, West, & Black, 2015).
  • Nutritional Education: Nutritional education is essential to raise awareness about the importance of a balanced diet, especially among vulnerable populations (Hamulka, Wadolowska, Hoffmann, Kowalkowska, & Gutkowska, 2018).
  • Access to Nutritious Foods: Public policies that ensure access to nutrient-rich foods, such as fruits, vegetables, and proteins, are crucial to reducing malnutrition and associated mental health issues (Darmon & Drewnowski, 2008).

Conclusion

Malnutrition impacts not only the body but also the mind. Deficiencies in essential nutrients increase the risk of depression, anxiety, and cognitive decline, severely affecting quality of life. Investing in a nutrient-rich diet is a crucial step in promoting mental health at all stages of life.

References

Bailey, R. L., West, K. P., Jr, & Black, R. E. (2015). The epidemiology of global micronutrient deficiencies. Annals of Nutrition & Metabolism, 66 Suppl 2(Suppl. 2), 22–33. doi:10.1159/000371618

Benton, D. (2010). The influence of dietary status on the cognitive performance of children. Molecular Nutrition & Food Research, 54(4), 457–470. doi:10.1002/mnfr.200900158

Chrzastek, Z., Guligowska, A., Sobczuk, P., & Kostka, T. (2023). Dietary factors, risk of developing depression, and severity of its symptoms in older adults-A narrative review of current knowledge. Nutrition (Burbank, Los Angeles County, Calif.), 106(111892), 111892. doi:10.1016/j.nut.2022.111892

Darmon, N., & Drewnowski, A. (2008). Does social class predict diet quality? The American Journal of Clinical Nutrition, 87(5), 1107–1117. doi:10.1093/ajcn/87.5.1107

FAO. (2022, July 6). The state of food security and nutrition in the world 2022. doi:10.4060/cc0639en

Grantham-McGregor, S., Cheung, Y. B., Cueto, S., Glewwe, P., Richter, L., Strupp, B., & International Child Development Steering Group. (2007). Developmental potential in the first 5 years for children in developing countries. Lancet, 369(9555), 60–70. doi:10.1016/S0140-6736(07)60032-4

Hamulka, J., Wadolowska, L., Hoffmann, M., Kowalkowska, J., & Gutkowska, K. (2018). Effect of an education program on nutrition knowledge, attitudes toward nutrition, diet quality, lifestyle, and body composition in Polish teenagers. The ABC of healthy eating project: Design, protocol, and methodology. Nutrients, 10(10), 1439. doi:10.3390/nu10101439

Laird, E. J., O’Halloran, A. M., Molloy, A. M., Healy, M., Hernandez, B., O’Connor, D. M. A., … Briggs, R. (2023). Low vitamin B12 but not folate is associated with incident depressive symptoms in community-dwelling older adults: a 4-year longitudinal study. The British Journal of Nutrition, 130(2), 268–275. doi:10.1017/S0007114521004748

Lee, H.-S., Chao, H.-H., Huang, W.-T., Chen, S. C.-C., & Yang, H.-Y. (2020). Psychiatric disorders risk in patients with iron deficiency anemia and association with iron supplementation medications: a nationwide database analysis. BMC Psychiatry, 20(1), 216. doi:10.1186/s12888-020-02621-0

Lu, S., Perez, L., Leslein, A., & Hatsu, I. (2019). The relationship between food insecurity and symptoms of Attention-Deficit Hyperactivity Disorder in children: A summary of the literature. Nutrients, 11(3), 659. doi:10.3390/nu11030659

Parker, G., Gibson, N. A., Brotchie, H., Heruc, G., Rees, A.-M., & Hadzi-Pavlovic, D. (2006). Omega-3 fatty acids and mood disorders. The American Journal of Psychiatry, 163(6), 969–978. doi:10.1176/ajp.2006.163.6.969

Prado, E. L., & Dewey, K. G. (2014). Nutrition and brain development in early life. Nutrition Reviews, 72(4), 267–284. doi:10.1111/nure.12102

Stabler, S. P. (2013). Vitamin B12Deficiency. The New England Journal of Medicine, 368(2), 149–160. doi:10.1056/nejmcp1113996

USDA. (2024). Key statistics & graphics. Retrieved November 3, 2024, from https://www.ers.usda.gov/topics/food-nutrition-assistance/food-security-in-the-u-s/key-statistics-graphics/

van Soest, A. P. M., de Groot, L. C. P. G. M., Witkamp, R. F., van Lent, D. M., Seshadri, S., & van de Rest, O. (2024). Concurrent nutrient deficiencies are associated with dementia incidence. Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association, 20(7), 4594–4601. doi:10.1002/alz.13884

WHO. (2021). World report on disability. Retrieved November 3, 2024, from https://www.who.int/teams/noncommunicable-diseases/sensory-functions-disability-and-rehabilitation/world-report-on-disability

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